The important marks and essential characteristics of China's exploration geochemistry are big information and systematic science of the earth. The overall development of exploration geochemistry persists in the policy of laying equal stress on resources and environment, truly and actively reflects the historical locus of the development of national economy and society, and has typical significance in the field of science and technology. During the natural resources period, the connotations of geological work related to resources are from mineral resources, land resources to all natural resources, whereas the connotations of geological work related to environment are from geological environment, land environment to all natural environments which include life community of mountains, water, forests, cultivated land, lakes and grass. At the time when the Ministry of Natural Resources is established and geological work is faced with deep transformation, the author, following writing a comment on this problem in 2008, here makes another discussion on this topic in some aspects which are worthy of attention, such as big data information science and geochemical survey of natural resources, establishment of geochemical theoretical system and geochemical evaluation system for natural resources guided by systematic science of the earth, important scientific problems aimed at the field of natural resources, deepening geochemical application research and theoretical research, and establishment of perfect scientific system. The long-term aim of exploration geochemistry lies in revealing the situation of natural resources and natural environment, realizing scientific development, and rational utilization and integrated protection of the earth's resources by means of big data information and systematic science of the earth, thus creating an environment that mankind can harmoniously coexist with the earth. Therefore, the whole process of the development of China's exploration geochemistry will be permeated with transformation and upgrade. Geochemistry will emerge in national professional department and science and technology field with the multi-purpose and all-round appearance characterized by the role of systematic nature, comprehensive nature and integration as well as application practice, thus extremely expanding and deepening its role in economic and social development. With its technological advantages, exploration geochemistry will implement big survey, big data and big application strategy, establish big environment, big ecology and big earth outlook, and transform itself into big geology, big resources and big science, so as to provide a geochemical scheme for solving problems of natural resources and ecological environment and promote exploration geochemistry in the period of overall development from the advantages of big data information application and the height of systematic scientific theory to the realm of 'big geochemistry'.