Based on the 1:50 000 stream sediment survey of an area of 1 450 km² in Huzhong-Tahe area, the authors collected 9 576 samples. Through the analysis of the samples in combination with the regional geological setting, the authors summarized geochemical parameters of 13 kinds of elements, the probability distribution of element values and the correlation of the elements. Sb, Pb, Ag, As, Zn, Cu, W, Mo, Bi, Cr and Ni are enriched in various degrees, so it is possible for them to form ore deposits. Combined Mo and Pb anomalies can be used as geochemical indicator for Mo. Based on the anomaly combination of stream sediment survey, the authors carried out 1:10 000 soil geochemical exploration and conducted surface uncovering, which led to the discovery of a molybdenum orebody, which is 1.4 m in width, with Mo grade of 0.014% in the concentration center. This proves that the method has good application value for ore prospecting in Huzhong-Tahe forest coverage area.