The application of geophysical and geochemical anomaly characteristics and the integrated study of the evaluation criteria in the Qinling gold and lead-zinc polymetallic ore district can play the role of mutual supplement and mutual verification. Based on geochemical anomaly characteristics and geological environment of the exploration area, the authors hold that the major ore-forming elements are Au and Ag, with the existence of the polymetallic element superimposed anomalies of Au, Ag, As, Hg, Cu, Pb, Zn, W and Mo. The magnetism is relatively low, and the ore-bearing structural alteration zone has relatively high polarizability and low apparent resistivity. Nevertheless, in the geological section, the orebodies mostly exhibit high resistivity and highe polarization. Based on characteristics of ore-related and barren anomalies, the authors established geophysical and geochemical ore-prospecting criteria for the exploration area. It is proved that the integrated method can yield better ore-prospecting effects in the search for structural altered rock type gold deposits in Qinling region.