The electromagnetic and human interference in the Tailong geothermal test area of Qianbei (northern Guizhou) platform uplift on the Yangtze metaplatform has restricted the exploration effect of the traditional electromagnetic method. Based on a comprehensive evaluation of interference sources and rock physical parameters obtained from the experimental zone, the authors carried out high precision deep wide-area electromagnetic detection experiments, conducted two-dimensional continuum source inversion, and obtained underground stratigraphic resistivity distribution regularity and characteristics at the depth of 5 km, with lower Ordovician Meitan Formation, lower Cambrian Jindingshan Formation,, Mingxinsi Formation and Niutitang Formation as the low resistance cover layers of the experimental zone, the lower Ordovician Huayuan Formation, Tongzi Formation, Cambrian Loushanguan Formation, Shilengshui Formation, Gaotai Formation and Qingxudong Formation, and Sinian Dengying Formation as the high resistance layers for heat storage. The influence of the deep fracture structure on the heat storage layer was also revealed. The electrical layer revealed by the wide-area electromagnetic method is consistent with the information revealed by the drilling SZK1, and the results show that the wide-area electromagnetic method is an effective detection method in the strong geothermal interference zone of Qianbei platform uplift on the Yangtze paraplatform. The results obtained by the authors enrich the geothermal energy research results in northern Guizhou and provide geophysical parameters for further promotion of geothermal exploration in northern Guizhou.