There exist changes of magnetic anomaly on account of oblique magnetization in aeromagnetic interpretation, especially in low magnetic latitude. When the area of the aeromagnetic map compilation is very large, the anomaly characteristics of similar magnetic bodies can be very different if they separately lie in the south and in the north, which will increase the difficulty of the aeromagnetic interpretation. This paper deals with the application effect of the magnetic map of the reduction to the pole with zonation and different inclinations in the largearea aeromagnetic interpretation by integrating theory with practice.