The Tianmushan Mo ore district lies at the juncture between the southern margin of the North China Platform and the Qinling Fold System, near the Luanchuan-Minggang deep fault. Geological and geochemical characteristics of the ore deposit show a close relationship between the ore-forming elements and the rock bodies. Geochemical behaviors of the ore-forming elements assume evident zoning, suggesting fairly favorable prospects in search for Mo-polymetallic deposits. Based on an analysis and study of the geophysical-geochemical anomalies in Tianmushan area, this paper has dealt with the relationship between the geochemical anomalies and the ore bodies, summed up the ore-prospecting criteria for this area, and pointed out orientations for further ore-prospecting work.