Based on applying valley soil geochemical survey to ore prospecting in the Jiucaigou ore district, the authors found some valuable anomalies. Combined with ore-controlling factors such as strata, lithologic character and structure, the authors analyzed the prospecting potentiality of element geochemical anomalies of Au, Ag, As, Hg and Sb. Element anomalies of As, Hg and Sb can indicate gold mineralization. The prospecting direction was pointed out, and three key targets for ore-exploration were delineated. Later, every key target was verified by exploration and surface work. Ideal ore-prospecting results were achieved. This method has been proved to be effective in geological prospecting and exploration, which provides scientific evidence for further work.