On the basis of an integrated analysis of the data related to the regional gravity and aeromagnetic survey on the scales of 1∶200 000 and 1∶50 000 in southwestern Henan in combination with a detailed study of deep-buried structures and faults as well as characteristics of magmatic rocks in the study area, the authors delineated concealed or semi-concealed intrusive bodies and faults. Furthermore, researches on the relationship between the mineralization zone, intrusive rocks and the structures based on geological, geochemical and geophysical data revealed that the features of regional gravity and aeromagnetic fields are related to the mineralization zone, with the delineation of 9 prospective ore-forming areas. The results contribute important information to the prospecting for deep and concealed ore deposits in southwest Henan area.