Metallogenic model of ore deposits constitute one of the problems that have aroused much interest in research work. There exist a great variety of geological ore-prospecting models and patterns as well as a number of geochemical ore-prospecting models. Nevertheless, these models are generally established on the basis of primary halos of ore deposits. whereas regional geochemical anomaly models of ore deposits or orefields established on the basis of regional geochemistry are relatively rare. With the ore field as the basic research unit and the 1: 200000 regional geochemical data as the basis, the present paper has studied regional geological and geochemical environments for mineralization from regional geological setting of the orefield as well as distribution regularity of positive and negative regional geochemical anomalies of 39 elements. It has been discovered that the spatial distribution of anomaly associations of ore-forming elements, anomaly associations of indicator elements and anomaly associations of elements in metallogenic environments exhibits unique structural characteristics in the orefield. On such a basis, the present paper has put forward the concept of anomaly structural model and, furthermore, the regional geological-geochemical anomaly structural model of the Zijinshan orefield.