The synthetic information orefield-predicting model, a specialized model for 1:50000 ore prognosis, is studied in this paper. The basic train of thought, working procedure and some key technical problems (the establishment of geological conceptual model, extraction and synthesis of information, analysis of metallogenic regularity and compilation of model maps) for establishing the model are summarized. With case studies as examples, the paper points out that the establishment and application of such a model in1:50000 ore prognosis would considerably raise the reliability of ore prognosis.