The Fe-Cu-U mineralization in the Luzong area in Anhui Province occurs primarily within the syenite mass and along its contact zone with surrounding rocks. Effectively delineating the syenite mass using geophysical exploration methods is a scientific issue that needs to be addressed urgently for mineral exploration breakthroughs in the Luzong area. Therefore, based on 358 rock samples from scientific drilling borehole ZK01 at a burial depth of 2 012 m in the Luzong area, this study measured their petrophysical properties, including density, magnetism (magnetic susceptibility and remanent magnetization intensity), electrical properties (resistivity and polarizability), and elastic wave velocity. The results indicate that syenites manifested low density and weak magnetic characteristics, providing prerequisites for syenite identification through gravity and magnetic explorations in borehole ZK01 or similar geological conditions. The strata and syenite-monzonite masses in the borehole exhibited medium-to-high resistivity characteristics with nonsignificant differences, increasing the difficulties in electrical prospecting. The syenite-monzonite masses displayed lower compressional and shear wave velocities compared to the volcanic layer in the Zhuanqiao Formation, laying a foundation for distinguishing strata from rock masses through seismic exploration.