A new sampling layout and samples processing method was applied in the updating work of 1:250 000 regional geochemical data in Hami-Cihai iron deposit in Xinjiang. A number of anomalies of such elements as tungsten, molybdenum, zinc, gold, and silver were delineated and the detailed regional geochemical data were obtained. According to the regional geochemical survey, the metallogenic geological background was re-recognized based on the favorable metallogenic conditions. The authors have obtained some prospecting achievements, especially the discovery of Qingbaishan lead-zinc deposit in the Beishan metallogenic belt. The results obtained by the authors have broadened the exploration space of the Beishan metallogenic belt.