The importance of carrying out geophysical prospecting work in the old mines is discussed in this paper. From the effectiveness and the capability for problem-solving, the reasons for carrying out magnetic method, charge method, transient electromagnetic method of integrated geophysical methods test were analyzed in this paper. The characteristics of the collection of the geophysical information in the cognition of geology by using different methods, the relationship between mineralization space and orebody, and the validity of prospecting were discussed in detail. The using of the principle of integrated geophysical work was proposed, in which the deep edge serves as the space, and the hydrothermal activity patterns, tectonic zone and contact zone serve as the object, thus expanding the surface and making key breakthrough.