Based on geophysical and geochemical methods such as ground gamma-ray spectrometric survey, soil geochemistry profile survey and audio frequency magnetotelluric sounding survey, the authors investigated the uranium deposits in the shallow coverage areas in Xiwan area of Guyuan County. The surface anomaly information related to uranium mineralization was revealed by the ground gamma-ray spectrometric survey and soil geochemistry profile survey. The faults and the morphology of subvolcanic rhyolite were analyzed by audio frequency magnetotelluric sounding survey in the anomaly sectors. The blind uranium orebody was found, followed by drilling verification of the integrated anomalies. The conclusion of prediction has some indication significance for further ore-prospecting work in this area.