The soil geochemical characteristics of the Zengjiaxi copper-sliver mining area in Hunan have been systematically summarized through the geological mapping and soil geochemical survey on the scale of 1:10000 in this paper. The concentration clarke values and variation coefficients of W,As,Sb in soil are both high,which indicates that these elements were involved in mineralization. The association of main metallogenic elements consists of W, Sb, As and Au which can be used as the indicator elements for prospecting. Four soil geochemical anomaly belts were delineated based on the geological and heochemical analysis,and among them Ⅰ,Ⅲ-1 and Ⅳ anomaly belts have the better prospecting potential.