In this paper, the authors studied the de-noising method theories based on manual translation, linear interpolation fitting and EMD decomposition, compiled corresponding interactive and EMD decomposition de-noising programs, and then processed the measured MT data. Examples given in this paper show that the capacity of traditional remote reference method for removing the strong energy interference is limited, and simple application of interactive de-noising also has certain insufficiency. In contrast, EMD based on interactive de-noising can remove noise effectually and thus improve signal-noise ratio in the ore concentration area. Based on comparing the measured profile inversion results before and after de-noising processing, the authors point out that the false anomaly after de-noising processing can be effectively removed, and hence more accurate geological interpretation basis can be provided.