Heavy multiple waves in marine seismic exploration interfered by primary waves can't be fully attenuated, and these multiple waves make the seismic profile too illegible and also makes it difficult to easily interpret and trace the horizon. In view of such a situation, multiple wave forward modeling by simulating field operation on the given velocity horizon model was created. As there were only a few horizons in the mocked layer model, some factors such as sample in pace and extended radius that affected precise prediction of multiple wave model were analyzed and discussed. After that, reasonable processing parameters were optimized and applied to the real seismic data. The final results demonstrate that 3D SRME (Surface Related Multiple Elimination), which is better than 2D SRME, is capable of effectively suppressing multiple waves.