The study of the geochemical characteristics of Taxiu-Qushi'an area was based on the 1:50 000 stream sediment survey. The authors obtained plentiful regional geochemical survey data. Through mathematical statistics and concentration distribution, the authors carried out mathematical analysis of 17 elements and also discussed spatial distribution and composition relationship of elements by cluster and factor analysis. According to abnormal distribution and elements mineralization characteristics, the authors chose 4 mineralization prospective areas through optimization and, on such a basis, suggested that the Maridang-Aerganlongwa prospective area is the favorable area in search for W and Au, and the Muyanggou-Tuotougang prospective area is the favorable area in search for Au.