This study is aimed at searching for silver ore-prospecting target areas in Huoburenbudun area based on 1:50 000 soil geochemical survey data. In this paper, the potential Ag resources in the geochemical anomaly area were evaluated and predicted by the geochemical block model. In combination with regional metallogenic geological conditions and soil geochemical characteristics, the authors evaluated the index of geoaccumulation and delineated four prospecting target areas. Through field survey verification, silver orebodies and mineralized bodies were found in Target Ⅱand Target Ⅳ. Further detailed geological survey is necessary for confirming metallogenic province, with special attention paid to mineral survey of AgM13 anomaly.