Lying at the core part of Qinling orogenic belt, the Weishancheng Au-Ag polymetallic ore belt is a complex tectonic belt produced by repeated convergence, piecing together and welding of several strata and terrains which were formed in different tectonic settings and had their respective formation characteristics as well as independent deformation, metamorphic and tectonic evolutionary sequences. This paper has studied the ore-forming process of this ore belt and magmatic rocks, major vein rocks, wall rock alterations, trace elements and geochemical characteristics of various epochs, probed into the regularity of element enrichment and variation, and established geological-geochemical ore-prospecting criteria.