When there exists certain temperature difference, the single crystal ofpyrite will produce thermo-electrotrmotive force and assume four conductiontypes, i.e., p type, n-p type, p-n type and n type. Different conduction typesare closely related to physicochemical environments during the formation ofpyrite. There are three basic physicochemical factors that decide the condu-ction type of pyrite. Determine the thermo-electromotive force of pyrite, anddivide it by temperature difference between the two electrodes, we can getthermoelectric coefficient of pyrite. In different types of ore deposits, spatialdistributions of thermoelectric coefficients of pyrite are different. The thermo-electricity of pyrite might be used to predict concealed ore bodies, studymetallogenic zonality and evaluate denudation extent of ore deposits.