Abstract: To identify areas potentially rich in metal minerals, this study proposed a prospecting method based on tectono-geochemistry weak information extraction. After the exploration scope was determined, sampling points were arranged using a grid pattern, followed by chemical tests on the collected samples. Through static extraction, centrifugation, and dynamic extraction, weak tectono-geochemical information in the samples was extracted. Then, the distribution of metal minerals within fault zones was analyzed based on the extraction results, and thus metal mineral prospecting was completed. During the geological exploration in the Wuminggou-Baidungou area in the Wulonggou, Dulan County, Qinghai Province, the mineral structures within the exploration area were analyzed using extracted weak tectono-geochemical information. As a result, among the 17 fault zones identified, a 500 m long metal ore body was delineated in fault zone Ⅳ, six ore bodies with lengths ranging from 180 to 400 m were determined in fault zone Ⅵ, and two ore bodies with lengths ranging from 550 to 800 m were delineated in fault zone Ⅺ. The remaining ore bodies were identified as blind ore bodies. The application of tectono-geochemistry weak information extraction for metal mineral prospecting yielded significant achievements, meeting the practical needs of metal mineral exploration. This method can be widely applied to metal mineral prospecting in similar geological settings.