Abstract: The Songshunangou gold mining area in Qinghai Province is situated in the central part of the North Qilian metallogenic/orogenic belt. Two deposits have been identified in its eastern and western portions, with cumulative proven Au resources exceeding 34 t, establishing them as large-scale deposits. Moreover, the area holds significant potential for ore prospecting, necessitating an urgent need for research into prospecting orientations to support mineral exploration efforts. Hence, based on the anomaly analysis of 1∶10 000 soil geochemical survey data and employing the two-window moving average method, this study identified the anomaly distributions and enrichment patterns of 10 elements (i.e., Au, As, Sb, Hg, Cu, Pb, Zn, Ag, W, and Mo) in the area. By analyzing elemental geochemical anomaly data and integrating the geological conditions for mineralization, this study delineated composite anomaly zones in the area using the average contrast method, followed by anomaly assessments. The results indicate that Au is the primary ore-forming element in the area, characterized by strong enrichment and significant variability, suggesting high mineralization potential. Seven composite soil geochemical anomaly zones were delineated in the area, with zones HP-1, HP-2, and HP-5 demonstrating the greatest potential for mineral exploration. Engineering validation confirms the presence of two ore/mineralized bodies, with one exhibiting an ore thickness of 1.5 m and a gold grade of 0.57 g/t in zone HP-2 and the other featuring an ore thickness of 1.42 m and a gold grade of 1.67 g/t in zone HP-5. Overall, this study provides geochemical evidence for determining prospecting orientations in the Songshunangou gold mining area while offering a reference for the deployment of subsequent mineral exploration work in the area.