Abstract: Seismic wave forward modeling technology is widely used in shallow exploration.This method can combine geological model and seismic model organically to verify and guide the acquisition,processing and interpretation of seismic data.The deep reflection seismic profile detection technology based on the oil reflection seismic technology has been very mature after decades of development and application.But up to now,the application of seismic wave forward modeling in deep reflection seismic profile is very insufficient.In this paper,the deep reflection seismic profile across Sichuan Basin was used to carry out forward modeling.By comparing and fitting the horizon of forward simulation data and actual seismic data,the parameters such as velocity and horizon were constantly modified,and the final depth domain geological model was established,which provides more accurate stratigraphic information such as crustal thickness and Moho depth for structural profile.Through the geological model in depth domain,it is revealed that the angle of Neoproterozoic paleosubduction in the northwest margin of Yangtze plate was about 30 °,and the depth of subduction reached 60 km.