Cold lake landscape in Qinghai province is located in the area of eolian sand accumulation. Anomalies of most ore-forming elements in -40 mesh of stream sediments remarkably weaken or even disappear owing to the eolian sand disturbance. The research shows that the fractal dimension of ore-forming elements in the eolian sand disturbance part of stream sediments exhibits mutation character. The granularity factor coefficient was calculated according to the disturbance characterized by the mixture of flowing dene with fast dene. This coefficient seems to be a good index for the mixing quantity of eolian sand in stream sediments. The composition factor coefficient was also computed with fold function formula of function theory, which coincides with the regional experimental results. Thus, the sample media in regional geochemical exploration should be -4(or -10)～+40 mesh in cold lake landscape.